579 Results for "

Macaranga denticulata (Blume) Müll. Arg.

" in MedChemExpress (MCE) Product Catalog:
Products (579)

579 Results for "Macaranga denticulata (Blume) Müll. Arg." in MCE Product Catalog:

19
(R)-GNE-140
(R)-GNE-140
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19 Publications Verification
Cat. No.: HY-100742A
CAS No.: 2003234-63-5
Pureté:  99.73%
Target:  

Lactate Dehydrogenase Bacterial

Domaines de recherche:  

Cardiovascular Disease Infection Inflammation/Immunology Cancer

(R)-GNE-140 is a potent inhibitor of lactate dehydrogenase (LDH) A, B and C, with IC50 values of 3, 5 and 5 nM against LDHA, LDHB, LDHC, respectively. (R)-GNE-140 blocks the conversion of pyruvate to lactate, reduces lactate production and histone lysine lactylation, and inhibits glycolysis. (R)-GNE-140 attenuates cardiac hypertrophy, alleviates PM2.5-induced pulmonary inflammation and fibrosis, blocks MRSA-induced Arg1 expression. (R)-GNE-140 is applicable to research related to pathological cardiac hypertrophy, pulmonary fibrosis, MRSA infection and pancreatic cancer .
11
Z-Gly-Gly-Arg-AMC
Z-Gly-Gly-Arg-AMC
0 Images
11 Cited Publications
Cat. No.: HY-P0019
CAS No.: 66216-78-2
Target:  

Fluorescent Dye Thrombin

Domaines de recherche:  

Cardiovascular Disease

Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .
11
Z-Gly-Gly-Arg-AMC acetate
Z-Gly-Gly-Arg-AMC acetate
0 Images
11 Cited Publications
Cat. No.: HY-P0019A
CAS No.: 2070009-61-7
Target:  

Fluorescent Dye Thrombin

Domaines de recherche:  

Others

Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .
11
PAβN dihydrochloride
PAβN dihydrochloride
0 Images
11 Cited Publications
Cat. No.: HY-101444A
CAS No.: 100929-99-5
Pureté:  99.89%
Synonyms: MC-207,110 dihydrochloride; Phe-Arg-β-naphthylamide dihydrochloride
Target:  

Bacterial

Domaines de recherche:  

Infection

PAβN dihydrochloride (MC-207110 dihydrochloride) is an efflux pump inhibitor.
10
Argipressin
Argipressin
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10 Cited Publications
Cat. No.: HY-P0049
CAS No.: 113-79-1
Synonyms: Arg8-vasopressin; AVP
Target:  

Vasopressin Receptor

Domaines de recherche:  

Neurological Disease Cancer

Argipressin (Arg8-vasopressin) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1.
10
Argipressin acetate
Argipressin acetate
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10 Cited Publications
Cat. No.: HY-W539944
CAS No.: 129979-57-3
Synonyms: Arg8-vasopressin acetate; AVP acetate
Target:  

Vasopressin Receptor Apoptosis

Domaines de recherche:  

Neurological Disease Cancer

Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1 .
9
Arg-Gly-Asp-Ser
Arg-Gly-Asp-Ser
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9 Cited Publications
Cat. No.: HY-12290
CAS No.: 91037-65-9
Pureté:  99.93%
Synonyms: RGDS peptide; Fibronectin tetrapeptide
Target:  

Integrin

Domaines de recherche:  

Inflammation/Immunology

Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1.
6
nor-NOHA monoacetate
nor-NOHA monoacetate
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6 Cited Publications
Cat. No.: HY-112885B
CAS No.: 2250019-93-1
Pureté:  99.96%
Synonyms: Nω-Hydroxy-nor-L-arginine monoacetate
Target:  

Arginase Apoptosis

Domaines de recherche:  

Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer

nor-NOHA monoacetate is a selective and reversible arginase inhibitor. nor-NOHA monoacetate induces apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA monoacetate has anti-leukemic activity. nor-NOHA monoacetate can used in study of endothelial dysfunction, immunosuppression and metabolism .
6
nor-NOHA acetate
nor-NOHA acetate
0 Images
6 Cited Publications
Cat. No.: HY-112885A
CAS No.: 1140844-63-8
Pureté:  98.81%
Synonyms: Nω-Hydroxy-nor-L-arginine acetate
Target:  

Arginase Apoptosis

Domaines de recherche:  

Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer

nor-NOHA acetate is a selective and reversible Arginase inhibitor. nor-NOHA acetate induces Apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA acetate has anti-leukemic activity. nor-NOHA acetate improves liver ischemia-reperfusion injury. nor-NOHA acetate can used in study of tuberculosis, endothelial dysfunction, immunosuppression and metabolism .
6
nor-NOHA dihydrochloride
nor-NOHA dihydrochloride
0 Images
6 Cited Publications
Cat. No.: HY-112885C
CAS No.: 291758-32-2
Pureté:  98.85%
Synonyms: Nω-Hydroxy-nor-L-arginine dihydrochloride
Target:  

Apoptosis Arginase

Domaines de recherche:  

Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer

nor-NOHA dihydrochloride is a selective and reversible Arginase inhibitor. nor-NOHA dihydrochloride induces Apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA dihydrochloride has anti-leukemic activity. nor-NOHA dihydrochloride improves liver ischemia-reperfusion injury. nor-NOHA dihydrochloride can used in study of tuberculosis, endothelial dysfunction, immunosuppression and metabolism .
3
GPRP acetate
GPRP acetate
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3 Cited Publications
Cat. No.: HY-P0074A
CAS No.: 157009-81-9
Synonyms: Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate
Target:  

Integrin

Domaines de recherche:  

Cardiovascular Disease

GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) .
3
GPRP
GPRP
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3 Cited Publications
Cat. No.: HY-P0074
CAS No.: 67869-62-9
Synonyms: Gly-Pro-Arg-Pro; Pefa 6003
Target:  

Thrombin

Domaines de recherche:  

Cardiovascular Disease

GPRP (Gly-Pro-Arg-Pro; Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction between fibrinogen and the platelet membrane glycoprotein Ⅱb/IIIa complex (glycoprotein IIb/IIIa receptor) . GPRP increases the level of free thrombin in activated platelet-rich plasma by reducing the adsorption of thrombin onto fibrin. GPRP inhibits platelet aggregation and prolongs the thrombin-initiated clotting time in plasma. GPRP is applicable for research related to thrombosis and thrombotic diseases .
2
Z-Arg-Arg-AMC hydrochloride
Z-Arg-Arg-AMC hydrochloride
0 Images
2 Cited Publications
Cat. No.: HY-134434
CAS No.: 136132-67-7
Pureté:  99.79%
Target:  

Cathepsin Fluorescent Dye

Domaines de recherche:  

Others

Z-Arg-Arg-AMC hydrochloride is a highly selective fluorescent Cathepsin B substrate. Z-Arg-Arg-AMC hydrochloride can be hydrolyzed by Cathepsin B to produce a fluorescent product for enzyme activity detection .
2
Arg-AMS
Arg-AMS
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2 Cited Publications
Cat. No.: HY-112862
CAS No.: 301351-95-1
Pureté:  ≥98.0%
Target:  

Aminoacyl-tRNA Synthetase

Domaines de recherche:  

Infection

Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes .
2
Cyclo(Arg-Gly-Asp-D-Phe-Cys)
Cyclo(Arg-Gly-Asp-D-Phe-Cys)
0 Images
2 Cited Publications
Cat. No.: HY-P2300
CAS No.: 862772-11-0
Synonyms: Cyclo(RGDfC)
Target:  

Integrin

Domaines de recherche:  

Cancer

Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors .
2
Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA
Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA
0 Images
2 Cited Publications
Cat. No.: HY-P2300A
Synonyms: Cyclo(RGDfC) TFA
Target:  

Integrin

Domaines de recherche:  

Cancer

Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC) TFA, a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA can be used in the research of tumors .
2
D-Arginine
D-Arginine
0 Images
2 Cited Publications
Cat. No.: HY-W016781
CAS No.: 157-06-2
Synonyms: H-D-Arg-OH
Category:  

Other Diseases Amino acids Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

D-arginine (H-D-Arg-OH) is the D-isomer of arginine. Arginine is an α-amino acid that is used in the biosynthesis of proteins. D-Arginine is an inactive form of L-arginine. D-arginine can be used in myeloma and neurological disease research . .
2
Sar-Arg-Val-Tyr-Val-His-NH2
Sar-Arg-Val-Tyr-Val-His-NH2
0 Images
2 Cited Publications
Cat. No.: HY-P2381
CAS No.: 2410957-04-7
Target:  

Angiotensin Receptor

Domaines de recherche:  

Others

Sar-Arg-Val-Tyr-Val-His-NH2 is a Gq-biased agonists, exhibits 10-fold larger molecular efficacies at the AT1R-Gq fusion protein compared with the AT1R-βarr2 fusion protein .
2
Mca-KPLGL-Dap(Dnp)-AR-NH2
Mca-KPLGL-Dap(Dnp)-AR-NH2
0 Images
2 Cited Publications
Cat. No.: HY-P4931
CAS No.: 720710-69-0
Target:  

MMP

Domaines de recherche:  

Cancer

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 . (Ex/Em=325 nm/400 nm)
2
PPACK dihydrochloride
PPACK dihydrochloride
0 Images
2 Cited Publications
Cat. No.: HY-122542A
CAS No.: 82188-90-7
Synonyms: Pebac; D-Phenylalanyl-prolyl-arginyl Chloromethyl Ketone; D-Phe-Pro-Arg-CH2Cl
Target:  

Protease Activated Receptor (PAR) Thrombin NF-κB

PPACK dihydrochloride is a potent, peptidic inhibitor targeting thrombin and granzyme GZMK. PPACK dihydrochloride specifically blocks the activities of thrombin and GZMK, thereby inhibiting thrombin-mediated PAR-1 cleavage, as well as downstream inflammatory and procoagulant signaling pathways. Through stabilizing IκB proteins, blocking NF-κB activation and reducing systemic levels of proinflammatory/procoagulant biomarkers, PPACK dihydrochloride exerts multiple effects including anti-inflammatory, antithrombotic, barrier repair, and inhibition of atherosclerotic plaque progression. PPACK dihydrochloride binds to platelets without interference from kininogen, effectively limiting acute thrombus growth and reducing eosinophil infiltration and goblet cell hyperplasia in asthma models. PPACK dihydrochloride is an important tool molecule for investigating the mechanisms of atherosclerosis, asthma and related thromboinflammatory diseases .
Assay Types